Pin it
If you're in the mood for a down-home, stick-to-your-ribs kind of dinner, this Old Fashioned Cattle Drive Casserole is exactly what you need. With layers of cheesy biscuit dough, taco-seasoned ground beef, fire-roasted tomatoes, and a creamy, melty cheese topping, it's no wonder this dish has taken off across kitchens and even on Cattle Drive Casserole TikTok. Whether you're making it for Sunday supper or need a satisfying dish that reheats like a dream, this casserole delivers comfort with every bite.
Think of it like a fusion between a taco bake, shepherd’s pie, and Southern biscuit casserole—all baked together until bubbling and golden. It’s a savory discovery that’s earned its spot on our regular dinner rotation. And the best part? It’s incredibly versatile. You can dress it up, switch out the protein, or even make a Cattle Drive Casserole with potatoes or Red Lobster biscuit mix. More on that below!
Why You’ll Love This Cattle Drive Casserole
- Bold & Hearty: Full of savory, cheesy layers and taco-inspired flavor.
- Crowd-Pleaser: Everyone—kids, adults, and even picky eaters—will dig in happily.
- Make-Ahead Friendly: Preps beautifully in advance, stores well, and reheats like a champ.
- Customizable: From slow cooker to skillet, you can make it your own in dozens of ways.
- Southern Vibes: A nod to Cattle Drive Casserole Pioneer Woman style with modern ease.
Ingredients
- 1 box cheddar biscuit mix: Or substitute with homemade or Red Lobster biscuit mix
- ½ cup shredded sharp cheddar cheese
- ⅓ cup milk: Or as directed on package
For the Beef Layer:
- 1 lb ground beef
- 1 small yellow onion, diced
- 1 poblano pepper, finely chopped (optional)
- 1 packet taco seasoning
- ½ tsp salt
- 1 (10 oz) can diced tomatoes with green chiles (undrained)
Creamy Topping:
- ¾ cup sour cream
- ⅓ cup mayonnaise
- 1 tsp smoked paprika
- 1 cup shredded Pepper Jack cheese
- 1 cup shredded sharp cheddar cheese
Optional Toppings: Fresh cilantro, sliced jalapeños, diced green onions, lime wedges, avocado slices
How to Make Cattle Drive Casserole (Oven Method)
Pin it
- Step 1: Preheat & Prepare the Biscuit Base
- Preheat your oven to 350°F (175°C). Grease a 9x13-inch baking dish. Mix biscuit ingredients and spread into dish. Bake for 8–10 minutes until lightly set.
- Step 2: Cook the Beef Filling
- In a skillet, brown beef with onion and poblano. Drain excess grease. Stir in taco seasoning, salt, and tomatoes. Simmer for 3–4 minutes.
- Step 3: Prepare the Creamy Cheese Topping
- Combine sour cream, mayo, smoked paprika, and both cheeses in a bowl. Mix until smooth.
- Step 4: Assemble the Layers
- Spread beef mixture over biscuit base. Top with creamy cheese mixture. Smooth out and sprinkle with extra cheese if desired.
- Step 5: Bake to Perfection
- Bake for 20–25 minutes until golden and bubbly. Let rest for 5–10 minutes before serving.
Cattle Drive Casserole Slow Cooker Method
Prepare the biscuit dough as drop biscuits and lightly cook. Layer cooked beef and cheese topping in slow cooker. Cook on low for 2.5–3 hours or high for 1.5 hours. Add biscuits in final 30 minutes for a crusty finish.
Want to Add Potatoes?
Swap out the biscuit base with 3–4 cups of mashed or thin-sliced potatoes. Assemble as directed and bake until heated through and golden on top.
Make It Your Own
- Protein: Ground turkey, shredded chicken, or plant-based meat work well.
- Add Veggies: Corn, bell peppers, black beans.
- Change the Base: Try crescent dough, cornbread, or cooked pasta.
- Cheese Options: Gouda, Monterey Jack, or Mexican blends all melt well.
Make-Ahead and Storage Tips
- Make-Ahead: Assemble unbaked, cover tightly, and refrigerate for up to 48 hours.
- Freezing: Wrap baked or unbaked in foil and freeze for up to 3 months.
- Reheating: Microwave individual portions or bake at 325°F until warmed through.
Pin it
What to Serve with Cattle Drive Casserole
- A green salad or slaw
- Cilantro lime rice
- Guacamole and chips
- Steamed green beans
- Corn on the cob
Final Thoughts
This easy Cattle Drive Casserole is the definition of a comfort classic. With layers of cheese, savory taco beef, and a creamy top that melts into every bite, it’s one of those dishes that never gets old. Whether you’re recreating the viral Cattle Drive Casserole TikTok version or putting your own twist on it, this recipe is sure to be a weeknight hit. Cozy, customizable, and downright delicious!
Frequently Asked Questions
Can I make this ahead of time? Yes! Assemble everything (without baking), cover, and refrigerate up to 48 hours before baking.
What can I use instead of biscuit mix? Crescent dough, mashed potatoes, or cornbread mix work well.
Can I freeze it? Absolutely. Wrap in foil and freeze either baked or unbaked for up to 3 months.
Can I make it vegetarian? Yes! Use a plant-based meat substitute and veggie additions like beans or corn.
Can I use different cheeses? Of course! Gouda, Monterey Jack, or even a spicy blend are great options.